منابع مشابه
Enzyme-Operated DNA-Based Nanodevices
Functional molecular nanodevices and nanomachines have attracted a growing interest for their potential use in life science and nanomedicine. In particular, due to their versatility and modularity DNA-based nanodevices appear extremely promising. However, a limitation of such devices is represented by the limited number of molecular stimuli and cues that can be used to control and regulate thei...
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Molecular recognition, programmability, self-assembling capabilites and biocompatibility are unique features of DNA. The basic approach of DNA nanotechnology is to exploit these properties in order to fabricate novel materials and structures on the nanometer scale. This cumulative dissertation deals with three aspects of this young research area: fast analysis, autonomous control of functional ...
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This paper describes some general techniques for transforming the design of a class of catalytic DNA nanodevices into the design for autocatalytic DNA nanodevices. Our techniques are particularly applicable to catalytic DNA nanodevices that act as detectors, where we would like their response to be sped up via autocatalytic behavior. We provide an example of this general scheme for design of au...
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Here we demonstrate that we can rationally and finely control the functionality of different DNA-based nanodevices and nanoswitches using electronic inputs. To demonstrate the versatility of our approach we have used here three different model DNA-based nanoswitches triggered by heavy metals and specific DNA sequences and a copper-responsive DNAzyme. To achieve electronic-induced control of the...
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DNA based nanostructures and devices are becoming ubiquitous in nanotechnology with rapid advancements in theory and experiments in DNA self-assembly which have led to a myriad of DNA nanodevices. However, the modeling methods used by researchers in the field for design and analysis of DNA nanostructures and nanodevices have not progressed at the same rate. Specifically, there does not exist a ...
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ژورنال
عنوان ژورنال: Nano Letters
سال: 2015
ISSN: 1530-6984,1530-6992
DOI: 10.1021/acs.nanolett.5b04566